As a single metric, follicle number per ovary best predicts PCOS. Ovarian volume and follicle number per single cross-section, together, provide the closest level of diagnostic potential to follicle number per ovary alone. Stromal measurements have little to no diagnostic potential.
In normal and polycystic ovary syndrome (PCOS) women, inhibin B production was decreased following recombinant hCG administration. These findings suggest that in PCOS women, androgen excess is not enhanced by LH-stimulated inhibin B production.
At 10-year follow-up, laparoscopic electrocautery in women with CC-resistant PCOS does not affect pregnancy complications or metabolic or cardiovascular disease later in life compared with ovulation induction with gonadotropins.
Baseline characteristics from 750 women with PCOS and their male partners from a multicenter trial show the groups to be well matched with body mass index exacerbating metabolic and reproductive parameters.
Motivation for sperm donation is multifaceted and primarily based on economic compensation and altruism. The attitudes toward aspects of donation remain liberal and unchanged among Danish sperm donors.
Proinflammatory cytokines are increased in menstrual effluents of women with chronic endometritis (CE). A test measuring interleukin-6 and tumor necrosis factor a might offer a reliable tool for screening CE.
The exceedingly low prevalence of uniparental disomy (UPD) indicates that routine preimplantation screening may not be necessary and that UPD is not a reasonable explanation to support hypothesized embryonic self-correction.
Oocyte cryopreservation was recently approved by the American Society for Reproductive Medicine (ASRM); however, most Society for Assisted Reproductive Technology (SART) member fertility clinics do not follow the SART/ASRM guidelines for web advertising of the procedure.
Male environmental BPA exposure may have an adverse influence on semen quality parameters, but does not affect embryo development at the blastocyst stage after IVF or intracytoplasmic sperm injection (ICSI).
In a healthy, multiethnic sample, a significant race/ethnicity-by-age interaction was observed, suggesting African-American women may have lower AMH at younger ages but experience less of a reduction in AMH with age.
In this international econometric study of assisted reproduction technology treatment, we show that the cost that consumers pay for treatment relative to income predicts the level of access and number of embryos transferred.
Trials sponsored by industry and nonindustry are systematically different, with industry supporting more placebo-controlled phase II/III trials. Trials launched without prior published preclinical results do not seem to fare well.
Maternal cell contamination often obscures accurate chromosome analysis of miscarriages, but testing can differentiate the maternal from fetal genome, thus improving detection of the true karyotype of pregnancy tissue.
A study comparing outcomes of induced versus spontaneous twins reveals higher risks of first-trimester bleeding, gestational diabetes, discordant growth, and cesarean section, with no other significant differences in obstetrical and puerperal complications.
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