This article discusses the advantages of the transvaginal approach for exogenous CSEP lesion resection and introduces the surgical procedure in detail.
Nerve growth factor is one of the key mediators that generates the pain associated with endometriosis. Dienogest inhibited NGF expression induced by TNF-α or IL-1β in human endometrial epithelial cells.
Rats with thin endometrium showed thicker endometrium and improved endometrial receptivity after BMSCs transplantation. The BMSCs have a beneficial effect on thin endometrium, and may play a role through migration and/or immunomodulatory properities.
Oxygen tensions can influence the growth patterns of endometriosis implants in a SCID mouse model. Hypoxia pretreatment promoted the proliferation and angiogenesis of endometriosis, whereas hyperoxia pretreatment demonstrated the opposite effect.
Nanoparticles formulated with superoxide dismutase, an antioxidant enzyme, were conjugated to an FSH peptide. Conjugation increased Sertoli cell uptake and improved cell survival after oxidative stress.
Tumor necrosis factor α, an early embryonic product, modulates endometrial epithelial cell migration and expression of milk fat globule–epidermal growth factor 8 protein (MFG-E8).
Results demonstrate the feasibility of using high-intensity focused ultrasound, under ultrasound imaging for guidance and monitoring, to induce localized thermal damage inside ovaries without damage to the ovarian surface.
Akt1 has a critical role in ovarian graft reception: although ovarian grafts lacking Akt1 activity survive the immediate posttransplantation period, long-term survival of the graft is impaired.
Black adolescents and adult women with PCOS have an increased risk of metabolic syndrome compared with their white counterparts. These findings differ from population-based controls and are independent of obesity in adults.
Antimüllerian hormone (AMH) exhibits an age-related decline, but the population distribution suggests that the current AMH Generation II assay standardization is not as reported by the manufacturer.
The menstrual pictogram (superabsorbent polymer-c version) is a simple semiquantitative method that can be used to diagnose heavy menstrual bleeding and would be suitable to test treatment effects in clinical trials.
The disturbance of TH17-Treg cell balance was involved in the immunopathogenesis of both diffuse and focal forms of adenomyosis and showed positive correlation with dysmenorrhea severity and CA-125 levels.
In a prospective cohort study, previous surgical skin scar characteristics could potentially predict the severity and extent of intra-abdominal adhesions at the time of laparoscopy.
Vaginal mifepristone may offer an effective treatment option for women with symptomatic uterine leiomyomas and can improve the patients’ quality of life.
Depending on the whole genome amplification used, the cell-cycle stage influences the accuracy of the comparative genome hybridization from single cells, because transitory gains and losses related to DNA replication are detected, such as segmental imbalances.
This is systematic review of uterus-sparing surgical treatment options for adenomyosis finds the techniques are feasible and efficacious for management of symptoms and preservation of fertility.
Linked public health and Society for Assisted Reproductive Technology Clinic Outcome Reporting System data sets identified deliveries to mothers with indicators of subfertility who did not undergo assisted reproductive technology (ART) to serve as a comparison group for ART outcomes research.
Semen quality parameters were associated with shorter and longer time to pregnancy (TTP) when modeled individually but not when modeled together. Male age was negatively associated with fecundity as measured by TTP.
In this retrospective cohort study, we measured vitamin D levels in 99 recipients of egg donation. Nonreplete vitamin D status [25(OH)D<30 ng/mL] was associated with lower clinical pregnancy and live-birth rates.
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