Lysine-specific demethylase 1 (LSD1) is overexpressed in endometriomas; treatment of endometriotic stromal cells with tranylcypromine, an LSD1 inhibitor, significantly reduces cellular proliferation, cell cycle progression, and invasiveness.

GSTO1, which is involved in the biotransformation process of arsenic, a well-known risk factor for pregnancy loss, is associated with recurrent miscarriage risk.

Ectopic pregnancy can occur after tubal sterilization, with the greatest risk for women sterilized before the age of 28 years or with laparoscopic electrodestruction or partial salpingectomy.

Women with a prior unilateral oophorectomy have compensatory follicular recruitment in the remaining ovary, and right ovaries respond better than left ovaries after stimulation for IVF.

A retrospective cohort study demonstrates that intramural fibroids with diameter larger than 2.85 cm have a negative effect on in vitro fertilization/intracytoplasmic sperm injection delivery rates.

Granulocyte colony-stimulating factor neither affects endometrial thickness nor pregnancy rates in normal in vitro fertilization patients.

Complication types and rates seem similar after transvaginal ultrasound–guided oocyte collection in in vitro maturation and conventionally stimulated in vitro fertilization cycles.

A retrospective study demonstrates differences in the kinetics between chromosomally normal and abnormal embryos, providing a selection tool that increases the probability of selecting normal embryos through a noninvasive method.

A literature search using the term “rescue ICSI” was performed. Thirty-eight studies were included, describing 1,863 patients and 194 offspring. Pregnancy rates and procedure safety are discussed.

The risk of monozygosity was higher with fresh day 5–6 embryos, donor oocytes, gonadotropin-releasing hormone agonist suppression, lower follicle-stimulating hormone doses, and assisted hatching (particularly day 2–3 embryos).

Progesterone (P) level at oocyte retrieval was inversely associated with pregnancy rates: as P levels increased, pregnancy rates decreased. The odds ratio for nonpregnancy was clinically significant when P was 12 ng/mL.

Cabergoline reduces the occurrence of moderate-severe ovarian hyperstimulation syndrome and probably does not have a clinically relevant impact on clinical pregnancy or on the number of retrieved oocytes.

The lowest aneuploidy risk is between ages 26–30, with higher prevalences in younger and older women, and 67% involve a single chromosome,with the ratio of trisomies/monosomies approximating 1.

Sperm retrieval in men undergoing microdissection testicular sperm extraction (micro-TESE) was not negatively affected by age. Men 50 years old who underwent successful micro-TESE were more likely to have larger testes.

Birefringence and MSOME are effective to select sperm with improved nuclear status. We found that sperm selected by both these methods and no nuclear vacuoles have significantly lower DNA fragmentation.

Better quality thawed human sperm was achieved after cryopreservation of high volumes compared with low volumes of specimens. Air volume in the straw had no influence on specimen quality.

The angled vas cutting forceps represents a modification of the straight cut technique and has the potential advantage of an increase in vasal surface area for reanastomosis and possible improvement of patency rates.

Reflections on “Age does not adversely affect sperm retrieval in men undergoing microdissection testicular sperm extraction,” by Ramasamy et al.

Education and enhanced awareness of the effect of age on fertility is essential in counseling the patient who desires pregnancy.

Direct-to-consumer genetic testing services for genealogical or ancestry purposes increases the risk 31 of inadvertently finding out that someone was conceived using gamete donation as well as 32 discovering the identity of the gamete donor(s).