This video presentation demonstrates the step-by-step microsurgical approach to the twolayered vasovasostomy technique by an experienced urologic microsurgeon.

This step-by-step video explains how to obtain, culture, and transfer blastocysts in order to study implantation and development using a new non-surgical method.

MFG-E8 and its receptor integrin avb3 are involved in the attachment of trophoblasts to the endometrial epithelium.

Diet and exercise interventions in obese founder males improve the reproductive health of male offspring, with a father’s metabolic and reproductive status predicting his son’s reproductive health.

Measurement of transcript levels in single human oocytes with the use of Nanostring and correlation with protein expression identified biologically meaningful oocyte-to-oocyte heterogeneity in functionally important regulatory pathways.

In an independent set of ovarian nongrowing follicle counts, the power model of ovarian nongrowing follicle depletion was determined to be an excellent fit to the observed counts.

Enzyme-linked immunosorbent assay measurement of antim€ullerian hormone (AMH) is a composite of inactive precursor and receptor-competent forms of AMH, which may confound its use for clinical assessment of ovarian function.

A factor analysis identified multiple factors that are responsible for the abnormalities associated with PCOS. Hyperandrogenemia was a common underlying feature of the metabolic and reproductive abnormalities in women with PCOS.

Patients with type 2 deiodinase (D2) Ala92Ala genotype, associated with an increased risk for diabetes, have decreased placental D2 activity that is not associated with dysglycemia or adverse gestational outcomes.

PAI-1 9785GA+AA, 844A/9785A, 4G/9785A, and 9785A/11053Gmay contribute to prevalence of primary ovarian insufficiency (POI) in Korean women.

This study demonstrates that distribution in metaphase I is nonrandom and influenced by chromosome size, gene density, and acrocentric chromosome morphology. Results support that some features defining chromosome territories are maintained during meiosis.

Neoadjuvant intra-arterial chemotherapy followed by total LRT may become a useful option for women with cervical cancer with a tumor size larger than 2 cm who wish to preserve fertility.

Electroejaculation and testicular sperm extraction led to successful sperm retrieval in 60% of adolescents and teenagers and 59% of adult men seeking fertility preservation before cancer therapy.

In slow-frozen/rapid-thawed ovarian tissue from cancer patients, a bioenergy/oxidative stress assessment based on confocal laser scanning microscopy allows identification of functionally preserved tissue.

In this meta-analysis including patients who underwent uterine preservation for endometrial neoplasia, oncologic and reproductive outcomes were not impaired in older patients with previous infertility or obesity.

Vitrification of ovarian tissue employing ethylene glycol and dimethyl sulfoxide in metallic grids preserves morphology of follicles and stroma, and maintains proliferation, viability, and vascularization status similarly to fresh tissue.

Knowledge regarding ovulation, fertility, and conception is limited in key areas among a sample of reproductive-age US women. Future initiatives should prioritize improved provider engagement and accurate information dissemination in Web-based venues.

Antioxidant intake and time to pregnancy (TTP) among couples treated for infertility was examined. Increased b-carotene, vitamin C, or vitamin E intakes are associated with shorter TTP in specific subgroups.

The most frequent etiology for bladder retention after surgery for deeply infiltrating endometriosis seems to be chronic bladder overdistention by insidious bladder overdistention.

The radical surgical resection of associated ileocecal andrectovaginal endometriosis reduces pelvicpain, constipation, and dyschezia during a long-term follow-up.

Lysine-specific demethylase 1 (LSD1) is overexpressed in endometriomas; treatment of endometriotic stromal cells with tranylcypromine, an LSD1 inhibitor, significantly reduces cellular proliferation, cell cycle progression, and invasiveness.

GSTO1, which is involved in the biotransformation process of arsenic, a well-known risk factor for pregnancy loss, is associated with recurrent miscarriage risk.

Ectopic pregnancy can occur after tubal sterilization, with the greatest risk for women sterilized before the age of 28 years or with laparoscopic electrodestruction or partial salpingectomy.

Women with a prior unilateral oophorectomy have compensatory follicular recruitment in the remaining ovary, and right ovaries respond better than left ovaries after stimulation for IVF.

A retrospective cohort study demonstrates that intramural fibroids with diameter larger than 2.85 cm have a negative effect on in vitro fertilization/intracytoplasmic sperm injection delivery rates.

Granulocyte colony-stimulating factor neither affects endometrial thickness nor pregnancy rates in normal in vitro fertilization patients.

Complication types and rates seem similar after transvaginal ultrasound–guided oocyte collection in in vitro maturation and conventionally stimulated in vitro fertilization cycles.

A retrospective study demonstrates differences in the kinetics between chromosomally normal and abnormal embryos, providing a selection tool that increases the probability of selecting normal embryos through a noninvasive method.

A literature search using the term “rescue ICSI” was performed. Thirty-eight studies were included, describing 1,863 patients and 194 offspring. Pregnancy rates and procedure safety are discussed.

The risk of monozygosity was higher with fresh day 5–6 embryos, donor oocytes, gonadotropin-releasing hormone agonist suppression, lower follicle-stimulating hormone doses, and assisted hatching (particularly day 2–3 embryos).

Progesterone (P) level at oocyte retrieval was inversely associated with pregnancy rates: as P levels increased, pregnancy rates decreased. The odds ratio for nonpregnancy was clinically significant when P was 12 ng/mL.

Cabergoline reduces the occurrence of moderate-severe ovarian hyperstimulation syndrome and probably does not have a clinically relevant impact on clinical pregnancy or on the number of retrieved oocytes.

The lowest aneuploidy risk is between ages 26–30, with higher prevalences in younger and older women, and 67% involve a single chromosome,with the ratio of trisomies/monosomies approximating 1.

Sperm retrieval in men undergoing microdissection testicular sperm extraction (micro-TESE) was not negatively affected by age. Men 50 years old who underwent successful micro-TESE were more likely to have larger testes.

Birefringence and MSOME are effective to select sperm with improved nuclear status. We found that sperm selected by both these methods and no nuclear vacuoles have significantly lower DNA fragmentation.

Better quality thawed human sperm was achieved after cryopreservation of high volumes compared with low volumes of specimens. Air volume in the straw had no influence on specimen quality.

The angled vas cutting forceps represents a modification of the straight cut technique and has the potential advantage of an increase in vasal surface area for reanastomosis and possible improvement of patency rates.

Reflections on “Age does not adversely affect sperm retrieval in men undergoing microdissection testicular sperm extraction,” by Ramasamy et al.

Education and enhanced awareness of the effect of age on fertility is essential in counseling the patient who desires pregnancy.

Direct-to-consumer genetic testing services for genealogical or ancestry purposes increases the risk 31 of inadvertently finding out that someone was conceived using gamete donation as well as 32 discovering the identity of the gamete donor(s).