Laparoscopic resection of a cesarean scar pregnancy has the advantages of shorter procedure duration, less blood loss, a shorter hospital stay, and faster recovery.

Human blastocysts secrete microRNAs into culture media, and MicroRNAs may be a noninvasive marker for delivery after in vitro fertilization.

We established a novel NOD/SCID murine xenograft model for uterine leiomyoma that reproduced histologic characteristics, sex steroid–dependent growth, and specific gene expression profiles of the original leiomyoma tissue.

After xenotransplantation, human primordial follicles can be matured to metaphase II oocytes even without stimulation. Administering human gonadotropin and GnRH agonist does not enhance the developmental capacity of oocytes in xenografts.

Contrary to previous assumptions, multi-oocyte follicles (MOFs) are frequently observed in the pubertal ovary. Follicle fusion, associated with granulosa cell invasiveness, appears to be the major mechanism for MOF generation.

Stimulation of mitochondria in embryos from older mice improved embryo viability and fetal weights and therefore may be a novel means of improving outcomes in an IVF setting.

Foxo3 is induced in cell and organ culture, and a mouse model, by 2-deoxyglucose (2-DG). In mice, 2-DG treatment results in reduced activation of primordial follicles.

Small molecules that specifically inhibit the canonical WNT/b-catenin pathway attenuate growth and proliferation of human uterine leiomyoma cell primary cultures.

Substantial variability in follicular fluid high-density lipoprotein particle components exist between follicles among women undergoing IVF as well as between women by age, BMI, race, smoking, and infertility diagnosis.

Our well-defined cohort provided comprehensive estimates of the features of metabolic and phenotypic profiles related to polycystic ovary syndrome in Korean women.

Transmission disequilibrium test analysis confirms that single-nucleotide polymorphism rs1501299 in ADIPOQ is significantly associated with risk of polycystic ovary syndrome in the Chinese population.

Dopamine receptor 2 agonists inhibit VEGF secretion in a dose-dependent fashion, which is directly dependent on the amount of D2 expressed by luteinized granulosa cells.

Although polycystic ovary syndrome is associated with metabolic risk, obesity was the major determinant for cardiometabolic disturbances in reproductive-aged women.

Overweight patients with infertility who underwent weight loss counseling and achieved meaningful weight loss (10%) had improved live birth rates compared with those who did not.

Three-dimensional sonohysterography—a minimally invasive and relatively inexpensive method with substantial interrater/intrarater agreement coefficients for the postoperative evaluation of the uterine cavity—is as diagnostically accurate as hysteroscopy.

Using longitudinal data on menstrual cycle function, we evaluated urinary cytokines levels for assessment of reproductive function by considering detection, variation across the menstrual cycle, and correlations with hormones.

Study reporting extensive preclinical validation and accuracy assessment of next-generation sequencing (NGS)-based comprehensive aneuploidy screening on single cells. NGS has demonstrated a robust methodology, ready for clinical application in reproductive medicine.

Women from low socioeconomic subgroups have higher placental resistance indices during the second and third trimester, which is mainly caused by smoking during pregnancy.

Select phthalates, but not bisphenol A, were associated with diminished couple fecundity as measured by a longer time to pregnancy in a longitudinally observed cohort recruited before conception.

Endometrium and endometriotic lesions express high levels of antim€ullerian hormone and its receptor, without any contribution to circulatory levels.

This observational study shows that comparative genomic hybridization and reflex microsatellite analysis are effective DNA technologies to determine chromosome results of preserved miscarriage tissue.

The perinatal outcome of twin pregnancies after early transvaginal fetal reduction from triplets is equivalent to the outcome of nonreduced twin pregnancies.

Concurrent estrogen action enhances the progestin-induced growth inhibition of ovarian endometrioma epithelial cells via up-regulation of progestin receptor B expression in oral contraceptives.

Based on recent U.S. summary data, donor oocyte recipients have stable rates of pregnancy outcomes before age 45, after which there is a small but steady and significant decline.

In patients who conceive twin pregnancies using IVF, oocyte donation increases the risk of gestational hypertension and preeclampsia.

The authors analyzed the gender of more than 100,000 babies in the United Kingdom born after ART and found that the type of ART treatment used can affect the sex ratio.

Methods for calculating gestational age in assisted reproductive technology and spontaneous deliveries can differ. Estimates of preterm birth rates can be influenced by these differences.

The delayed-start protocol improves ovarian response in poor responders by enhancing, promoting, and synchronizing follicle development.

There is very little evidence of an overall benefit of cervical mucus removal before embryo transfer for women undergoing in vitro fertilization/intracytoplasmic sperm injection.

After 1,157 fresh and 645 vitrified-warmed day-5 single-blastocyst transfers, we found vitrified warmed blastocysts yielded equivalent birth rates and improved neonatal outcomes compared with fresh transfers.

Prolonged exposure to preovulatory P elevation in frozen–thawed embryo transfer cycles in natural cycles adversely affected the pregnancy rates, similar to the fresh stimulated IVF treatment cycles.

Among men attending a fertility clinic, low-fat dairy intake, particularly low-fat milk, was related to higher sperm concentration and progressive motility, whereas cheese intake was related to lower sperm concentration.

A profile of the user with anabolic steroid–induced hypogonadism is provided, and management strategies are proposed.

A pilot trial of a novel circumcision device to facilitate safe, single-visit surgical circumcision in five patients from the Veterans Administration Puget Sound Healthcare System.

In a retrospective cohort study of azoospermic patients, the full operating characteristics of follicle stimulating hormone were determined to allow for proper education of patients and individualized treatment based on specific risk.

Cystic fibrosis transmembrane-conductance regulator mutations were observed to have higher prevalence in men with congenital bilateral absence of vas deferens and were associated with increased risk of miscarriage and stillbirth.

Reflections on “Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth” by Ono et al.

Reflections on “Development and validation of a next-generation sequencing–based protocol for 24-chromosome aneuploidy screening of embryos” by Yeh et al.

Reflections on “Development and validation of a next-generation sequencing–based protocol for 24-chromosome aneuploidy screening of embryos” by Fiorentino et al.

Reflections on “Pregnancy outcomes decline in recipients over age 44: an analysis of 27,959 fresh donor oocyte in vitro fertilization cycles from the Society for Assisted Reproductive Technology” by Yeh et al.