Laparoscopic resection of a cesarean scar pregnancy has the advantages of shorter procedure duration, less blood loss, a shorter hospital stay, and faster recovery.
We established a novel NOD/SCID murine xenograft model for uterine leiomyoma that reproduced histologic characteristics, sex steroid–dependent growth, and specific gene expression profiles of the original leiomyoma tissue.
After xenotransplantation, human primordial follicles can be matured to metaphase II oocytes even without stimulation. Administering human gonadotropin and GnRH agonist does not enhance the developmental capacity of oocytes in xenografts.
Contrary to previous assumptions, multi-oocyte follicles (MOFs) are frequently observed in the pubertal ovary. Follicle fusion, associated with granulosa cell invasiveness, appears to be the major mechanism for MOF generation.
Stimulation of mitochondria in embryos from older mice improved embryo viability and fetal weights and therefore may be a novel means of improving outcomes in an IVF setting.
Foxo3 is induced in cell and organ culture, and a mouse model, by 2-deoxyglucose (2-DG). In mice, 2-DG treatment results in reduced activation of primordial follicles.
Small molecules that specifically inhibit the canonical WNT/b-catenin pathway attenuate growth and proliferation of human uterine leiomyoma cell primary cultures.
Substantial variability in follicular fluid high-density lipoprotein particle components exist between follicles among women undergoing IVF as well as between women by age, BMI, race, smoking, and infertility diagnosis.
Our well-defined cohort provided comprehensive estimates of the features of metabolic and phenotypic profiles related to polycystic ovary syndrome in Korean women.
Transmission disequilibrium test analysis confirms that single-nucleotide polymorphism rs1501299 in ADIPOQ is significantly associated with risk of polycystic ovary syndrome in the Chinese population.
Dopamine receptor 2 agonists inhibit VEGF secretion in a dose-dependent fashion, which is directly dependent on the amount of D2 expressed by luteinized granulosa cells.
Although polycystic ovary syndrome is associated with metabolic risk, obesity was the major determinant for cardiometabolic disturbances in reproductive-aged women.
Overweight patients with infertility who underwent weight loss counseling and achieved meaningful weight loss (10%) had improved live birth rates compared with those who did not.
Three-dimensional sonohysterography—a minimally invasive and relatively inexpensive method with substantial interrater/intrarater agreement coefficients for the postoperative evaluation of the uterine cavity—is as diagnostically accurate as hysteroscopy.
Using longitudinal data on menstrual cycle function, we evaluated urinary cytokines levels for assessment of reproductive function by considering detection, variation across the menstrual cycle, and correlations with hormones.
Study reporting extensive preclinical validation and accuracy assessment of next-generation sequencing (NGS)-based comprehensive aneuploidy screening on single cells. NGS has demonstrated a robust methodology, ready for clinical application in reproductive medicine.
Women from low socioeconomic subgroups have higher placental resistance indices during the second and third trimester, which is mainly caused by smoking during pregnancy.
Select phthalates, but not bisphenol A, were associated with diminished couple fecundity as measured by a longer time to pregnancy in a longitudinally observed cohort recruited before conception.
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