The latest debate about the contraceptive mandate within the U.S. Affordable Care Act (ACA) and the recommendations in the listing of recommended basic benefits by the Institute of Medicine (IOM) have struck me as quite odd.
Cryopreservation and delayed embryo transfer Assisted reproductive technology registry and reporting implications
Some assisted reproductive technology cycles designated as “embryo banking” have been excluded from public reports. The Society for Assisted Reproductive Technology and the Centers for Disease Control and Prevention have collaborated to recapture these cycles.
The success rates after frozen-thawed embryo transfer are nearing those of fresh transfer in assisted reproductive technology cycles. Randomized controlled trials should determine whether fresh transfers should be abandoned.
Frozen transfer allows embryos to implant and develop in a more physiologic environment. This review summarizes the research on the effect of the superovulated environment on implantation and embryo development.
Frozen embryo transfer is now competitive with fresh transfer and may be superior in some cases. Numerous factors should be considered when deciding between them.
The rationale to freeze all embryos to avoid transfer into a supraphysiologic environment to improve safety and efficacy is compelling, but not yet proven. How do we decide?