The function of luminal epithelia appears to differ from that of glandular epithelia, even though both cell types are continuous in the functionalis layer of the endometrium.
17b-estradiol unbalances the expression of SCF and c-kit in rat seminiferous tubules cultured ex vivo, which is accompanied by reduced proliferation and augmented apoptosis of germ cells.
Because Cyp17a1 expression level was increased in the theca interna and interstitial cells in pinealectomized rats receiving vehicle, melatonin may influence CYP17A1 expression and steroidogenesis in the ovaries.
Leiomyoma and myometrial cells in three-dimensional leiomyoma cultures treated with liarozole resulted in decreased expression of transforming growth factor b3 (TGF-b3) and TGF-b3-regulated extracellular matrix.
Lipoxin A4 regulates expression of estrogen receptor b (ERb) and inhibits 17b-estradiol induced p38 MAPK phosphorylation very likely through ERb in human endometriotic stromal cells.
Interleukin-25 expression was enhanced by trophoblast-derived hCG, could stimulate the proliferation of DSCs through activating JNK and AKT signals, which finally contributes to the establishment and maintenance of physiological pregnancy.
In primary prevention practice, HOMA-M120 and Sib (Avignon et al.) seem to adequately replace the euglycemic-hyperinsulinemic clamp in lean and overweight/obese PCOS patients, respectively.
Ovaries from Indian women seem to age at an earlier stage than those of Spanish women. We observed a 6-year difference between Indian and Spanish women.
Standard average FSH profiles do not reflect the more complex dynamics of daily hormonal variations. Discrepancies between the average profile and individual variants may be used to detect abnormalities.
Age-specific antimullerian hormone (AMH) references were determined in women with and without polycystic ovary syndrome (PCOS). AMH levels were higher in women with PCOS than in those without PCOS. AMH correlated well with age and antral follicle count.
Semen cryopreservation is an option to preserve fertility and should be offered to all pubertal boys diagnosed with cancer. If masturbation fails, electroejaculation can be considered as a useful option for semen cryopreservation.
Tubal ligation, hysterectomy, and unilateral oophorectomy were independently associated with lower risks of ovarian cancer. The associations with tubal ligation and hysterectomy are stronger for nonserous tumors.
Cumulative exposure to active smoking was associated with reduced fecundability among current and former smokers. Time since smoking cessation and passive smoking were not appreciably associated with fecundability.
Two or more acts of intercourse during the peri-implantation window is associated with a lower probability of pregnancy given prior intercourse during the fertile window.
Loss of CD26/dipeptidyl peptidase IV under hypoxia (low oxygen tension) and the subsequent increase in migratory and angiogenic factors may favor conditions for lesion development in endometriosis.
Laparoscopic ureteral shaving for deep endometriosis can be safely and effectively accomplished, with a low risk of complications, encouraging fertility outcomes and a low probability of disease relapse.
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