July 2014

In the secretory endometrium of women luminal epithelia exhibit gene and protein expressions that differ from those of glandular epithelia

The function of luminal epithelia appears to differ from that of glandular epithelia, even though both cell types are continuous in the functionalis layer of the endometrium.

Fertility and Sterility

Jul 01, 2014

July 2014

Estrogenic regulation of testicular expression of stem cell factor and c kit Implications in germ cell survival and male fertility

17b-estradiol unbalances the expression of SCF and c-kit in rat seminiferous tubules cultured ex vivo, which is accompanied by reduced proliferation and augmented apoptosis of germ cells.

Fertility and Sterility

Jul 01, 2014

July 2014

Melatonin influences on steroidoigenic gene expression in the ovary of pinealectomized rats

Because Cyp17a1 expression level was increased in the theca interna and interstitial cells in pinealectomized rats receiving vehicle, melatonin may influence CYP17A1 expression and steroidogenesis in the ovaries.

Fertility and Sterility

Jul 01, 2014

July 2014

Preeclampsia is associated with a deficiency of lipoxin A4 An endogenous anti inflammatory mediator

Lipoxin A4 deficiency may result in preeclampsia because of changes in inflammation, oxidative stress, and 11b-HSD2 expression.

Fertility and Sterility

Jul 01, 2014

July 2014

Liarozole inhibits transforming growth factor β3 mediated extracellular matrix formation in human three dimensional leiomyoma cultures

Leiomyoma and myometrial cells in three-dimensional leiomyoma cultures treated with liarozole resulted in decreased expression of transforming growth factor b3 (TGF-b3) and TGF-b3-regulated extracellular matrix.

Fertility and Sterility

Jul 01, 2014

July 2014

Lipoxin A4 regulates expression of estrogen receptor and inhibits 17β-estrodiol induced p38 mitogen activated protein kinase phosphorylation in human endometriotic stromal cells

Lipoxin A4 regulates expression of estrogen receptor b (ERb) and inhibits 17b-estradiol induced p38 MAPK phosphorylation very likely through ERb in human endometriotic stromal cells.

Fertility and Sterility

Jul 01, 2014

July 2014

Interleukin 25 induced by human chorionic gonadotrophin promotes the proliferation of decidual stromal cells by activation of JNK and AKT signal pathways

Interleukin-25 expression was enhanced by trophoblast-derived hCG, could stimulate the proliferation of DSCs through activating JNK and AKT signals, which finally contributes to the establishment and maintenance of physiological pregnancy.

Fertility and Sterility

Jul 01, 2014

July 2014

Assessment of insulin resistance in lean women with polycystic ovary syndrome

In primary prevention practice, HOMA-M120 and Sib (Avignon et al.) seem to adequately replace the euglycemic-hyperinsulinemic clamp in lean and overweight/obese PCOS patients, respectively.

Fertility and Sterility

Jul 01, 2014

July 2014

Ethnicity as a determinant of ovarian reserve Differences in ovarian aging between Spanish and Indian women

Ovaries from Indian women seem to age at an earlier stage than those of Spanish women. We observed a 6-year difference between Indian and Spanish women.

Fertility and Sterility

Jul 01, 2014

July 2014

Characterization of follicle stimulating hormone profiles in normal ovulating women

Standard average FSH profiles do not reflect the more complex dynamics of daily hormonal variations. Discrepancies between the average profile and individual variants may be used to detect abnormalities.

Fertility and Sterility

Jul 01, 2014

July 2014

Age specific serum antimüllerian hormone levels in women with and without polycystic ovary syndrome

Age-specific antimullerian hormone (AMH) references were determined in women with and without polycystic ovary syndrome (PCOS). AMH levels were higher in women with PCOS than in those without PCOS. AMH correlated well with age and antral follicle count.

Fertility and Sterility

Jul 01, 2014

July 2014

Genetic variants in the RABL2A gene in fertile and oligoasthenospermic infertile men

Among RABL2A genetic variants in male infertility, the 114391996 delC variant may confer a risk for oligoasthenospermia in Australian men.

Fertility and Sterility

Jul 01, 2014

July 2014

New insights into the expression profile and function of micro ribonucleic acid in human spermatozoa

Human spermatozoa contain a stable population of miRNAs potentially related to embryo development and spermatogenesis.

Fertility and Sterility

Jul 01, 2014

July 2014

Interleukin 1β 511T C genetic variant contributes to recurrent pregnancy loss risk and peripheral natural killer cell proportion

IL-1b -511CC genotype was associated with increased recurrent pregnancy loss risk and peripheral natural killer cell proportion.

Fertility and Sterility

Jul 01, 2014

July 2014

Electroejaculation as a method of fertility preservation in boys diagnosed with cancer A single center experience and review of the literature

Semen cryopreservation is an option to preserve fertility and should be offered to all pubertal boys diagnosed with cancer. If masturbation fails, electroejaculation can be considered as a useful option for semen cryopreservation.

Fertility and Sterility

Jul 01, 2014

July 2014

Tubal ligation hysterectomy unilateral oophorectomy and risk of ovarian cancer in the Nurses Health Studies

Tubal ligation, hysterectomy, and unilateral oophorectomy were independently associated with lower risks of ovarian cancer. The associations with tubal ligation and hysterectomy are stronger for nonserous tumors.

Fertility and Sterility

Jul 01, 2014

July 2014

Active and passive smoking and fecundability in Danish pregnancy planners

Cumulative exposure to active smoking was associated with reduced fecundability among current and former smokers. Time since smoking cessation and passive smoking were not appreciably associated with fecundability.

Fertility and Sterility

Jul 01, 2014

July 2014

Peri implantation intercourse lowers fecundability

Two or more acts of intercourse during the peri-implantation window is associated with a lower probability of pregnancy given prior intercourse during the fertile window.

Fertility and Sterility

Jul 01, 2014

July 2014

CD26 DPPIV downregulation in endometrial stromal cell migration in endometriosis

Loss of CD26/dipeptidyl peptidase IV under hypoxia (low oxygen tension) and the subsequent increase in migratory and angiogenic factors may favor conditions for lesion development in endometriosis.

Fertility and Sterility

Jul 01, 2014

July 2014

Laparoscopy for ureteral endometriosis Surgical details long term follow up and fertility outcomes

Laparoscopic ureteral shaving for deep endometriosis can be safely and effectively accomplished, with a low risk of complications, encouraging fertility outcomes and a low probability of disease relapse.

Fertility and Sterility

Jul 01, 2014

July 2014

Dynamics of nitric oxide altered follicular microenvironment and oocyte quality in women with endometriosis

Women with endometriosis undergoing assisted reproductive technology have increased nitrate and peroxynitrite in the oocyte microenvironment concurrent with adverse impact on maturation and aging of immature oocytes.

Fertility and Sterility

Jul 01, 2014

July 2014

Ultrasound mapping system for the surgical management of deep infiltrating endometriosis

A new ultrasonographic mapping system for evaluating the extent of deep endometriosis may be useful for preoperative planning and intraoperative management of symptomatic patients.

Fertility and Sterility

Jul 01, 2014

July 2014

Trophoblast retrieval and isolation from the cervix for noninvasive prenatal screening at 5 to 20 weeks of gestation

Fetal cells retrieved by endocervical cytobrush at 5–20 weeks of pregnancy and isolated with immunomagnetic nanoparticles are extravillous trophoblast cells that contain intact fetal DNA useful for prenatal testing.

Fertility and Sterility

Jul 01, 2014

July 2014

Identifying risk factors for recurrent cesarean scar pregnancy A case control study

This is a case-control study of risk factors for recurrent cesarean scar pregnancy. Findings on risk factors might be helpful for the prevention and early diagnosis of the disease.

Fertility and Sterility

Jul 01, 2014

July 2014

Conjugated bisphenol A in maternal serum in relation to miscarriage risk

Conjugated bisphenol A level in maternal serum at the time of missed menses is associated with increased risk of euploid and aneuploid miscarriage in an infertile population.

Fertility and Sterility

Jul 01, 2014

July 2014

Long term influence of combined oral contraceptive use on the clinical course of relapsing remitting multiple sclerosis

This retrospective assessment of long-term effects of combined oral contraceptives (COCs) on relapsing–remitting multiple sclerosis showed that COC use is associated with reduced disability progression and reduced evolution to secondary-progressive multiple sclerosis.

Fertility and Sterility

Jul 01, 2014

July 2014

A randomized controlled pilot trial on the effect of dehydroepiandrosterone on ovarian response markers ovarian response and in vitro fertilization outcomes in poor responders

No significant improvement in ovarian response markers, ovarian response to standard dose gonadotropin stimulation, or IVF outcomes was detected in poor responders receiving pretreatment DHEA compared with placebo.

Fertility and Sterility

Jul 01, 2014

July 2014

First successful pregnancy in a globozoospermic patient having homozygous mutation in SPATA16

A healthy child was born to a patient with globozoospermia and a homozygous mutation to the SPATA16 gene.

Fertility and Sterility

Jul 01, 2014

July 2014

Diminished ovarian reserve is the predominant risk factor for gonadotropin releasing hormone antagonist failure resulting in breakthrough luteinizing hormone surges in in vitro fertilization cycles

Patients who fail to remain suppressed in response to GnRH antagonists have significantly poorer ovarian reserve compared with patients who do not experience breakthrough LH surges.

Fertility and Sterility

Jul 01, 2014

July 2014

Live birth from a 46 year old using fresh autologous oocytes through in vitro fertilization

We report a live birth with in vitro fertilization from a 46-year-old woman using autologous oocytes.

Fertility and Sterility

Jul 01, 2014

July 2014

Human oocyte cryopreservation with slow freezing versus vitrification Results from the National Italian Registry data 2007 2011

In 14,328 oocyte cryopreservation procedures and 1,850 pregnancies reported to the National Italian Registry from 2007 to 2011, vitrification shows a higher pregnancy rate per started cycle than slow freezing.

Fertility and Sterility

Jul 01, 2014

July 2014

What makes them split Identifying risk factors that lead to monozygotic twins after in vitro fertilization

In vitro fertilization increases MZT incidence; young oocytes, year of IVF cycle, and extended culture (embryo stage) confer the greatest risk. Specific assisted reproductive technology procedures may also contribute, although their impact correlates more with chorionicity.

Fertility and Sterility

Jul 01, 2014

July 2014

Does prolonged pituitary down regulation with gonadotrophin releasing hormone agonist increase live birth rate in in vitro fertilization treatment?

In a comparison of the regular long protocol with a prolonged protocol with 28-days’ down-regulation, a significantly higher live-birth rate (55.56% vs. 45.73%) was observed with the prolonged protocol.

Fertility and Sterility

Jul 01, 2014

July 2014

Nomograms for predicting changes in semen parameters in infertile men after varicocele repair

We formulated nomograms to predict improvements in semen parameters (total motile count, sperm concentration, motility, and morphology) after varicocele repair using multivariable linear regression.

Fertility and Sterility

Jul 01, 2014

July 2014

Decreased expression of SAM68 in human testes with spermatogenic defects

Deficient expression of SAM68 might be one of the factors involved in the mechanism underlying spermatogenic defects. These results may offer new perspectives on the molecular basis of abnormal spermatogenesis.

Fertility and Sterility

Jul 01, 2014

July 2014

Raman spectroscopy as an ex vivo noninvasive approach to distinguish complete and incomplete spermatogenesis within human seminiferous tubules

Raman spectroscopy may noninvasively identify different maturational stages of spermatogenesis in ex vivo human seminiferous tubules.

Fertility and Sterility

Jul 01, 2014

July 2014

Urinary metabolome identifies signatures of oligozoospermic infertile men

The urinary metabolome could differentiate oligozoospermic infertile men from fertile men. The disrupted metabolic pathways reflected fertility reduction that may be tightly associated with energy consumption and antioxidant defenses in spermatogenesis.

Fertility and Sterility

Jul 01, 2014

July 2014

Ethics of uterus transplantation with live donors

Before launching live donor liver transplantation in Chicago, the preparations included thorough ethical discussion, which was subsequently published in The New England Journal of Medicine.

Fertility and Sterility

Jul 01, 2014

July 2014

Preterm births multiples and fertility treatment Recommendations for changes to policy and clinical practices

Each year nearly one in eight infants in the United States is born preterm. Preterm birth places babies at increased risk for death, health problems including long-term neurological disabilities, and extended time in the hospital.

Fertility and Sterility

Jul 01, 2014

July 2014

Has noninvasive fetal trisomy testing rung the death knell for other forms of prenatal testing

Obstetric vigilance for early pregnancy screening has become imperative for all pregnancies, regardless of the risk for chromosomal anomalies.

Fertility and Sterility

Jul 01, 2014