Vitamin D plays an important role in steroidogenesis, follicular development, ovarian reserve measures/markers, and IVF outcome. Vitamin D might have a beneficial reproductive effect in vitamin D–deficient women with polycystic ovary syndrome.
Based on a cohort of 372 women with a history of recurrent early pregnancy loss, obesity was associated with euploid miscarriage, which is a known risk factor for subsequent miscarriage.
Elevated early follicular progesterone levels and in vitro fertilization outcomes A prospective intervention study and meta analysis
Elevated progesterone levels on cycle day 2 affect ongoing pregnancy rates in gonadotropin-releasing hormone antagonist cycles.
Sperm content of postacrosomal WW binding protein is related to fertilization outcomes in patients undergoing assisted reproductive technology
Sperm content of the postacrosomal head protein PAWP is positively correlated with successful fertilization and normal preimplantation embryonic development after intracytoplasmic sperm injection.
Cost effectiveness analysis comparing continuation of assisted reproductive technology with conversion to intrauterine insemination in patients with low follicle numbers
In patients with 4 mature follicles during controlled ovarian stimulation, it is more cost effective to proceed with oocyte retrieval than to convert to intrauterine insemination.
Efficacy and safety of intrauterine insemination and assisted reproductive technology in populations serodiscordant for human immunodeficiency virus A systematic review and meta analysis
A systematic review and meta-analysis for outcomes with intrauterine insemination and in vitro fertilization for HIV-serodiscordant couples found no seroconversions and similar outcomes to HIV-seronegative infertility patients.
Lag time from ovulation trigger to oocyte aspiration and oocyte maturity in assisted reproductive technology cycles A retrospective study
The proportion of metaphase II oocytes increases up to a 35-hour lag time between oocytematuration trigger and aspiration and then stabilizes up to 38 hours.
Follicular phase ovarian follicular fluid and plasma cytokine profiling of natural cycle in vitro fertilization patients
Follicular fluid cytokine concentrations vary throughout the follicular phase in the natural cycle and demonstrate complex interrelationships that underpin normal folliculogenesis and subsequent oocyte and embryo development.
Dual trigger with gonadotropin releasing hormone agonist and standard dose human chorionic gonadotropin to improve oocyte maturity rates
We report on how a dual trigger of GnRH-a and hCG improves the percentage of mature oocytes retrieved in patients with a history of low oocyte maturity.
Pregnancy rates in donor oocyte cycles compared to similar autologous in vitro fertilization cycles An analysis of 26457 fresh cycles from the Society for Assisted Reproductive Technology
We discuss how data from the Society for Assisted Reproductive Technology registry suggests that fresh autologous stimulation decreases endometrial receptivity in a model that compares donor oocyte cycles with similar autologous cycles.
Blastulation rates decline in a linear fashion from euploid to aneuploid embryos with single versus multiple chromosomal errors
Euploid embryos are far more likely than aneuploid embryos to progress to the blastocyst stage with a linear decrease in probability of blastulation with increasing number of chromosomal abnormalities.
In a large sample, no increased rate of autism spectrum disorder (ASD) associated genetic events in ASD subjects conceived by assisted reproduction compared to ASD subjects conceived without assisted reproduction.
A meta-analysis of the literature regarding youth varicocele and semen outcomes demonstrates an overall negative effect of varicocele on semen, and improvement of semen parameters following varicocele treatment.
The objective of this study was to identify male molecular causes of fertilization failures. Samples were analyzed by proteomic analysis. Two proteins involved in gametic interaction were identified: LR67 receptor and xylulose reductase.
This study shows differences in mRNA levels of the transcription factors LXRs and some of their downstream genes in testes of men with nonobstructive azoospermia and obstructive azoospermia.
Resistin interleukin 6 tumor necrosis factor alpha and human semen parameters in the presence of leukocytospermia smoking habit and varicocele
Semen resistin is correlated with inflammatory cytokines and sperm quality; in cases of leukocytospermia and smoking habits, conditions with an inflammatory basis, the concentrations of resistin are increased.
Why are we still 20 years later depriving human immunodeficiency virus serodiscordant couples of equal access to fertility care
Reflections on “Efficacy and safety of intrauterine insemination and assisted reproductive technology in populations serodiscordant for human immunodeficiency virus: a systematic review and meta-analysis” by Barnes et al.
This guideline document reviews the safety and efficacy of assisted hatching.
Number of embryos for transfer following in vitro fertilization or intracytoplasmic sperm injection Summary of a Cochrane review
A policy of repeated single embryo transfer may minimize the risk of multiple pregnancy without substantially reducing live birth rates.
We have an opportunity as clinicians to identify patients with endometriosis that have the potential for malignant transformation. Future efforts should be focused on developing effective and noninvasive screening tools to identify these patients and possible nonsurgical treatment options, such as long-term tolerable suppressive medical therapy.