The technique of transanal disc excision using the Contour® Transtar™ stapler is applied in deep endometriotic nodules of the lower and mid rectum, thus specifically avoiding low colorectal resections.

Elective surgical intervention for women with Mayer- Rokitansky-K€uster-Hauser syndrome and uterine remnant leiomyomas can prevent the complication of torsion as well as prevent ovarian resection in premenopausal women.

Tranilast reduces fibronectin, COL1A1, versican, and activin-A expression in leiomyoma and myometrial cells.

The ability of murine ovarian hormone synthesis became abnormal and the ovarian tissue behaved insulin resistance, after treated with dexamethasone, in vivo and in vitro; the Chinese herbal extract cryptotanshinone was found to partially antagonize their behavior.

Sperm involved in recurrent partial hydatidiform mole pregnancies is not able to activate human oocytes or trigger the normal pattern of Ca2+ oscillations in mouse and human oocytes in vitro.

ITGA6, EPCAM, and THY1 are markers for enriching human SSCs using FACS, but only ITGA6 is suitable for MACS.

Sorting long-term cultured human testicular cells for ITGA6 is an efficient strategy for enrichment of spermatogonial stem cells (SSC) and important for further characterization before clinical application of SSC autotransplantation.

Vismodegib is a novel oral medication that targets the hedgehog pathway to treat basal cell carcinoma. Amenorrhea secondary to vismodegib is due to blockading of FSH-R signaling.

Serum hepcidin levels are increased in polycystic ovary syndrome women and correlated with iron excess and metabolic disorder, but not with BMP-6 expression in granulosa cells.

Female veterans are at high risk of sexual assault in their lifetimes, which may increase their risk of infertility and the chance they will delay, forego, or terminate a pregnancy.

A cross-sectional analysis of 193 men in California found an inverse association between perceived stress and sperm concentration, motility, and morphology. Associations for stressful life events were similar.

The prevalence of uterine mullerian duct anomalies has not previously been studied in a randomly selected general population. By saline contrast sonohysterography a prevalence of 9.8% was found.

Considering both efficacy and patient preference, oral administration may be the optimal route for misoprostol administration.

Anovulation prevalence among eumenorrheic women varies greatly by algorithm. Urinary LH surge algorithms, such as used in fertility monitors, identified more anovulatory cycles compared with methods utilizing serum P.

Polymorphisms in the vitamin D pathway (rs12800438 near DHCR7 and rs6058017 in ASIP) were associated with fibroid risk, supporting the hypothesis that vitamin D deficiency is involved in fibroid etiology.

DNA sequencing and single nucleotide polymorphism association analyses in 2,271 endometriosis cases and 2,163 controls provide further evidence that variants in CYP2C19 contribute to endometriosis susceptibility in both familial and sporadic cases.

In nonmenopausal breast cancer patients, tamoxifen effectively reduces cancer risk despite chronically extremely high E2 levels. Tamoxifen co-administration during conventional COH for IVF is effective without increasing risks to patients.

The hypersensitive PicoAMH assay, by its capacity to detect low levels of blood AMH, allows a more accurate prediction of menstrual cycle recovery in young women after chemotherapy.

We describe the feasibility of human uterus retrieval from brain dead donors. Uterus retrieval could be part of a reproducible multiorgan procurement procedure. Uterus donation seems readily accepted.

This study estimates the prevalence and temporal trends of male factor infertility diagnoses within ART clinics in the United States from 1999–2010, and maps the geographic distribution.