Optimal adult human SSC recovery is achieved with testicular cell suspension cryopreservation, whereas similar fetal SSC recovery was achieved with both tissue and single cell suspension cryopreservation.

Mammalian target of rapamycin signaling pathway regulates spermatogonial stem cell differentiation via stimulated retinoic acid gene 8 (Stra8).

We demonstrate that nucleolar channel systems are present during the window of endometrial receptivity previously identified by their transcriptomic signature using the endometrial receptivity array.

Dopamine receptor 2 agonist prevents vascular permeability in an ovarian hyperstimulation syndrome rat model by decreasing ovarian vascular endothelial growth factor production.

Prenatally androgenized rats had aberrant metabolic and polycystic ovary morphology similar to human polycystic ovary syndrome (PCOS). Changesof DNA methylation may be an important factor for epigenetic programming of PCOS during development.

A rhesus monkey model indicates that repeated controlled ovarian hyperstimulation could potentially affect the development and function of ovarian cells in the long term.

Women with hyperandrogenic polycystic ovary syndrome (PCOS) show a more unfavorable cardiometabolic profile compared with women with nonhyperandrogenic PCOS. However, screening for cardiovascular risk factors is crucial in all women with PCOS.

More-severe menstrual pain is associated with lower antimullerian hormone concentration among Japanese women age 20–22 years who had never used oral contraceptives; the effect persisted even after adjustment for menstrual-cycle regularity.

Polycystic ovary morphology according to the modified Rotterdam criteria in a nongynecologic cohort in our study is less common than previously reported. Transabdominal ultrasound may be a useful tool in the evaluation of polycystic ovary syndrome, even in obese adolescents.

Experiences of CBRC clinical care received by participants were generally rated positive in terms of treatment costs, safety, and information provided, although counseling needs being met were rated less favorably.

In a population-based sample, infertility treatment as recorded on the birth certificate was not associated with symptoms of postpartum depression.

Although posthumous assisted reproduction (PAR) appears to be acceptable to a majority of IVF users, further research is required on how to ensure that their consent for PAR is well informed.

The first series of pregnancies achieved after UPA treatment is reported.

Pain in hysteroscopy is related to the presence of synechiae in the cervical canal, to the duration of the procedure, and to the use of normal saline as a distension medium.

This study demonstrated that the rs10965235 single-nucleotide polymorphism in the CDKN2B-AS gene and the rs16826658 single-nucleotide polymorphism near the WNT4 gene were significantly associated with endometriosis in a Korean population.

A novel microarray platform was developed offering the possibility of combined aneuploidy screening, genetic fingerprinting, and mitochondrial DNA (mtDNA) assessment of embryos. Associations between mtDNA and maternal age are reported.

Fertility preservation patients report higher levels of depression and anxiety at the onset of treatment than infertility patients, but infertility patients’ symptoms worsen across treatment.

Reproductive endocrinology and infertility practices in areas with a higher percentage of Hispanics are more likely to translate into Spanish. Practices with a translated website use social media more often.

Japan’s recent temperature fluctuation seems to be linked to a lower male:female ratio of newborns, partly via increased male fetal deaths, suggesting vulnerability ofmale concepti to external stresses, including climate changes.

Dydrogesterone supplementation in women with recurrent pregnancy loss improves ongoing pregnancy rates.

As the complexity of operations has increased in the IVF laboratory, a new look at staffing requirements is needed.

Frozen-thawed embryo transfer has been associated with a significantly lower risk of ectopic pregnancy (EP) compared with fresh cycles. Ovarian stimulation might be associated with an increased risk of EP.

There is a significant association between the embryo quality parameters reported to the Society for Assisted Reproductive Technology Clinic Outcome Reporting System and live birth.

Controlled ovarian hyperstimulation with intrauterine insemination may be futile for infertile couples of any age with follicle stimulating hormone levels of 10–15 mIU/mL and estradiol 40 pg/mL.

Female cystic fibrosis (CF) carrier status does not appear to impact the chance of achieving pregnancy with assisted reproductive technology (ART). Further research is needed to investigate whether positive CF carrier status affects fertility in a non-ART context.

Our data demonstrated no difference in euploid blastocyst rates between presumed fertile and infertile patients. Pregnancy and implantation rates were significantly higher in presumed fertile patients when transferring euploid blastocysts.

Starting ovarian stimulation on days 2 or 15 of the menstrual cycle yielded similar oocyte numbers in same oocyte donors with encouraging pregnancy rates in recipients of the vitrified oocytes.

The policy of limitless nondonor in vitro fertilization– embryo transfer cycles in Israel should be questioned and further assessed.

This study investigated the prevalence and significance of reverse cleavage by human embryos observed via time-lapse monitoring. Embryos showing reverse cleavage were associated with compromised subsequent development and implantation potential.

An alternative strategy for embryo selection based on a multivariable morphokinetic model combined with continuous incubation in an integrated timelapse monitoring system improves the clinical results.

Diagnostic testis biopsy in nonobstructive azoospermia has little value, even when uniform Sertoli cell–only pattern is seen. When both testis volume and follicle-stimulating hormone are considered, sperm retrieval rates are 7%–45%.

Sperm acrosome reaction is impaired in obese men, showing a reduced response to P and an elevated spontaneous component, which may affect sperm fertilization potential.

In this large cohort study of 10,665 men, semen quality, including volume, sperm concentration, and progressive motility, decreased with increased body mass index. Morphology was unaffected.

Palmitoylethanolamide and oleoylethanolamide in human seminal plasma may preserve sperm functions and disturbances in their normal functioning by exocannabinoids found in Cannabis, could result in male reproductive failure.

Reflections on “Motivations and experiences of patients seeking cross border reproductive care: the Australian and New Zealand context,” by Rodino et al.

Reflections on “Spanish-language content on reproductive endocrinology and infertility practice websites,” by Londra et al."

Controlled ovarian hyperstimulation (COH) is considered a key factor in the success of IVF-ET because it enables the recruitment of multiple healthy fertilizable oocytes and, thereby, multiple as opposed to single ET. COH usually includes the coadministration of gonadotropins and GnRH analogues; the two most commonly used protocols are the long GnRH agonist suppressive protocol and the multiple-dose GnRH antagonist COH protocol.

An international collaboration of endometriosis research and biobanking experts developed standard operating procedures for the collection, processing, and storage of biological tissue samples in endometriosis and control subjects to allow large-scale collaborative research.

An international collaboration of endometriosis research and biobanking experts developed standard operating procedures for the collection, processing, and storage of biological fluid samples in endometriosis patients and controls to allowlarge-scale collaborative research.

An international collaboration of endometriosis research and biobanking experts has developed standardized means of recording clinical and covariate phenotypic information in endometriosis and control patients to allow large-scale collaborative research.