An adverse uterine nutritional environment during pregnancy results in premature reproductive senescence in adult rats.

A simple perfusion apparatus was designed, constructed, and tested for safely and securely culturing, testing, and visualizing oocytes and embryos for longitudinal analysis with minimal handling.

Spermatogenesis can be destroyed by alkylating chemotherapies. In this study, spermatogenesis and undifferentiated spermatogonia in mice treated with busulfan were protected by treatment with granulocyte colony-stimulating factor.

Use of a gonadotropin-releasing hormone agonist trigger during in vitro fertilization results in similar hormone profiles, mature oocyte yield, and pregnancy outcomes in women with polycystic ovarian syndrome when compared with other high responders.

Among euthyroid patients undergoing IUI, TSH level was not associated with cycle parameters or clinical pregnancy rate. TSH level was inversely related to the odds of spontaneous abortion.

We discuss how follicular fluid cortisol levels may regulate cumulus cell lipolysis during oocyte meiotic resumption and affect oocyte quality during in vitro fertilization.

A mixed-method study of 129 lesbian mothers found that most were satisfied with their choice 18 years previously of a known, open-identity, or unknown sperm donor.

Except for the most commonly cited fertility and gynecology journals, reporting guidelines are uncommonly requested from the authors. Also, accomplishment of CONSORT items was suboptimal in randomized controlled trials.

Polycystic ovary syndrome patients who are overweight or obese showed increased serum leptin levels. High leptin levels may reduce g-epithelial Naþ channel expression in human endometrium via activating the STAT3 pathway, resulting in attenuated endometrial receptivity.

In the majority of patients with Mayer-Rokitansky-K€uster syndrome, a functional vagina could be created by Frank dilation and Davydov neovaginoplasty with the use of a peritoneal graft.

In an assessment of the presence of copy number variations (CNV) in men presenting with meiosis arrest and azoospermia, we detected two unique CNVs and several in known meiosis genes.

The reproductive outcomes of oocyte donation from women cured of cancer are similar to those from women without previous cancer, regardless of cancer type.

Nine women with uterine factor infertility underwent live-donor uterus transplantation. The seven cases with viable uteri after 12 months are presented, with special reference to menstruation, blood flow, rejection, and immunosuppression.

The high intake of saturated and trans-fats was positively related to asthenozoospermia. Dietary omega-3 polyunsaturated fatty acids are dose dependently and inversely associated with reduced odds of asthenozoospermia.

We observed in a prospective United States cohort study that higher environmentally relevant serum perfluorooctanoic acid concentrations before pregnancy were significantly associated with a greater risk of gestational diabetes.

We discuss that in monitoring the safety and efficacy of fertility treatment, registration of the percentage of single embryo transfer cycles might not be sufficient and utilization should be taken into account as well.

Molybdenum and several other metals were associated with altered testosterone in men, which may have important implications as altered testosterone has been linked to many adverse health effects.

Endometriosis is associated with a substantial economic burden during the 5-year periods both before and after diagnosis; healthcare utilization and costs peak during the first year after diagnosis among endometriosis patients.

A fetal pelvic mass was diagnosed at 35 weeks’ gestation and removed on day of life 2, revealing endometriosis. This case provides some support for theories on the pathophysiology of neonatal endometriosis

Overexpression of MIF, CD74, and COX-2 genes in ectopic endometrium and macrophage migration inhibitory factor protein in blood serum of endometriosis patients can be considered as a molecular biomarker for endometriosis development and pathophysiology.