An adverse uterine nutritional environment during pregnancy results in premature reproductive senescence in adult rats.

A simple perfusion apparatus was designed, constructed, and tested for safely and securely culturing, testing, and visualizing oocytes and embryos for longitudinal analysis with minimal handling.

Spermatogenesis can be destroyed by alkylating chemotherapies. In this study, spermatogenesis and undifferentiated spermatogonia in mice treated with busulfan were protected by treatment with granulocyte colony-stimulating factor.

Use of a gonadotropin-releasing hormone agonist trigger during in vitro fertilization results in similar hormone profiles, mature oocyte yield, and pregnancy outcomes in women with polycystic ovarian syndrome when compared with other high responders.

Among euthyroid patients undergoing IUI, TSH level was not associated with cycle parameters or clinical pregnancy rate. TSH level was inversely related to the odds of spontaneous abortion.

We discuss how follicular fluid cortisol levels may regulate cumulus cell lipolysis during oocyte meiotic resumption and affect oocyte quality during in vitro fertilization.

A mixed-method study of 129 lesbian mothers found that most were satisfied with their choice 18 years previously of a known, open-identity, or unknown sperm donor.

Except for the most commonly cited fertility and gynecology journals, reporting guidelines are uncommonly requested from the authors. Also, accomplishment of CONSORT items was suboptimal in randomized controlled trials.

Polycystic ovary syndrome patients who are overweight or obese showed increased serum leptin levels. High leptin levels may reduce g-epithelial Naþ channel expression in human endometrium via activating the STAT3 pathway, resulting in attenuated endometrial receptivity.

In the majority of patients with Mayer-Rokitansky-K€uster syndrome, a functional vagina could be created by Frank dilation and Davydov neovaginoplasty with the use of a peritoneal graft.

In an assessment of the presence of copy number variations (CNV) in men presenting with meiosis arrest and azoospermia, we detected two unique CNVs and several in known meiosis genes.

The reproductive outcomes of oocyte donation from women cured of cancer are similar to those from women without previous cancer, regardless of cancer type.

Nine women with uterine factor infertility underwent live-donor uterus transplantation. The seven cases with viable uteri after 12 months are presented, with special reference to menstruation, blood flow, rejection, and immunosuppression.

The high intake of saturated and trans-fats was positively related to asthenozoospermia. Dietary omega-3 polyunsaturated fatty acids are dose dependently and inversely associated with reduced odds of asthenozoospermia.

We observed in a prospective United States cohort study that higher environmentally relevant serum perfluorooctanoic acid concentrations before pregnancy were significantly associated with a greater risk of gestational diabetes.

We discuss that in monitoring the safety and efficacy of fertility treatment, registration of the percentage of single embryo transfer cycles might not be sufficient and utilization should be taken into account as well.

Molybdenum and several other metals were associated with altered testosterone in men, which may have important implications as altered testosterone has been linked to many adverse health effects.

Endometriosis is associated with a substantial economic burden during the 5-year periods both before and after diagnosis; healthcare utilization and costs peak during the first year after diagnosis among endometriosis patients.

A fetal pelvic mass was diagnosed at 35 weeks’ gestation and removed on day of life 2, revealing endometriosis. This case provides some support for theories on the pathophysiology of neonatal endometriosis

Overexpression of MIF, CD74, and COX-2 genes in ectopic endometrium and macrophage migration inhibitory factor protein in blood serum of endometriosis patients can be considered as a molecular biomarker for endometriosis development and pathophysiology.

Involvement of the urinary tract is frequent in patients with deep infiltrating endometriosis, and the probability of ureteral involvement is in linear correlation to the size of endometriotic rectovaginal nodules.

Through a case-control study, the GRIM-19 deficiency in the villus was found may be associated with missed abortion via increasing apoptosis and affecting angiogenesis.

We discuss a cost-effectiveness analysis demonstrating that immediate postpartum intrauterine device placement is a cost-effective method of contraception compared with routine placement and prevents unintended pregnancies.

Antimullerian hormone has weak association with implantation and clinical pregnancy rates in women undergoing ART, but its predictive ability for pregnancy rates is greatest in women with diminished ovarian reserve.

A comparison of controlled ovarian hyperstimulation outcomes between patients with polycystic ovarian morphology and concurrently treated and age-matched controls does not reveal any difference regarding oocyte quality.

The elevated progesterone on the day of human chorionic gonadotropin triggering has an obvious negative impact on pregnancy outcome only at extremely high progesterone concentrations.

Intravenous calcium infusion effectively reduced the incidence of ovarian hyperstimulation syndrome development without reduction in the pregnancy rate.

The association between blastocyst transfer and monozygotic twinning may be related to the high quality nature of the embryo cohort rather than the extended culture.

Women who give birth after experiencing infertility and undergoing assisted reproductive techniques are at higher risk for early breastfeeding cessation.

In a hospital-based cohort, intrauterine insemination and/or ovulation induction/stimulation was associated with increased risk of preterm birth at <37, <35, and

Very advanced maternal aged women using ART are more likely to be primiparous or undergo elective cesarean delivery, and are at increased risk of retained placenta. Oocyte source does not affect outcomes.

Delaying oocyte denudation or injection does not compensate for a suboptimal in vivo exposure to the follicular environment.

Men with medical comorbidities have a higher rate of abnormal semen parameters.

Men with “normal” semen results are vastly underrepresented in the referral population. Men with any semen parameter below the World Health Organization 2010 criteria demonstrated findings indicative of a global dysfunction in spermatogenesis.

Morphology levels in sperm assessments decreased over time, owing to changes in methodological factors, and male aging. No prognostic value was found for individual in vitro fertilization or intracytoplasmic sperm injection patients.

E2F1 gene dosage changes were identified in 7.3% of nonobstructive azoospermic men but rarely occur in the general population, suggesting a role for E2F1 in male fertility.

Reflections on “Urinary tract endometriosis in patients with deep infiltrating endometriosis: prevalence, symptoms, management and proposal for a new clinical classification” by Knabben et al.

Reflections on “Analysis of semen parameters in male referrals: impact of reference limits, stratification by fertility categories, predictors of change, and comparison of normal semen parameters in subfertile couples,” by Baker et al.

This document provides the latest recommendations for the use of a gestational carrier, including indications for this technique and the evaluation of carriers and intended parents.

A presentation at the Opening Ceremony of the ASRM Seventieth Annual Meeting reviews advances in reproductive medicine and presents an overview of the 2014 Strategic Plan: “Global Impact Through Dynamic Engagement."