Contained morcellation of uterine tissue is readily accomplished via a laparoscopic approach within an insufflated endoscopic pouch, or via ultraminilaparotomy using a flexible, self-retaining retractor.
An FSH receptor polymorphism (rs6166) affects the outcome of ovulation induction in normogonadotropic anovulatory subfertility. The minor allele (680Ser) is associated with Clomiphene-resistant anovulation during treatment with clomiphene citrate.
In this registry-based cohort study, we found positive associations between prospectively measured time to pregnancy and several adverse birth outcomes, including preterm birth, low birth weight, placental disorders, gestational diabetes, and cesarean section.
Twenty-four–chromosome preimplantation genetic diagnosis in translocation carriers yields a live birth rate of 52% per embryo transfer and 38% per biopsy cycle. Thirty percent of cycles had no euploid embryos.
Additional congenital abnormalities and regions of genomic imbalance are common in women with mullerian disorders, including Mayer-Rokitanksy-Kuster-Hauser syndrome. These women should be thoroughly investigated, and array comparative genomic hybridization should be considered.
Elevated TCS exposure may be associated with diminished fecundity. BPA and phthalates showed no negative impact; on the contrary, some phthalates might be associated with a shorter time to pregnancy. A major limitation of the study was that only one measurement of exposure was available for each woman after conception. Further research is necessary to test these findings.
This registry-based study suggests that the associations between IVF/ICSI and penoscrotal hypospadia and imprinting disorders reported in the literature are better explained by the underlying subfertility than by IVF/ICSI treatment.
P-selectin deficiency significantly retarded the development of endometriosis in a mouse model, and soluble P-selectin treatment markedly reduced lesion size in mice through decreased platelet aggregation and angiogenesis, resulting in reduced fibrotic tissue content.
MicroRNA expression profiles were significantly altered between miscarriage and normal pregnancy deciduas. MicroRNA-199b-5p and SGK1 were detected to determine their interaction in pregnancy maintenance in vivo and in vitro.
Singletons born to primiparous women using assisted reproductive technology had increased risk for preterm birth compared with those conceived spontaneously. The increased risk was observed along the gestational age continuum.
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