August 2015

All the papers from the August 2015 issue of Fertility and Sterility.

Human chorionic gonadotropin stimulates spheroid attachment on fallopian tube epithelial cells through the mitogen activated protein kinase pathway and down regulation of olfactomedin 1

Human chorionic gonadotropin increases the attachment of trophoblastic spheroids on human fallopian tube epithelial cells, through activation of extracellular signal regulated kinase and Wnt/b-catenin signaling pathways, leading to down-regulation of Olfm1 expression.

Expanded preconception carrier screening in clinical practice Opening Pandoras Box

Genetic testing for inherited genetic conditions is an important component of preconception planning, to assist in assessing the risk of genetic disease in a child, as well as anticipating the management of a woman’s reproductive care. Traditional methods of carrier screening have focused on panethnic screening for conditions including cystic fibrosis and spinal muscular atrophy, whereas other conditions, including hemoglobinopathies and Tay-Sachs, are screened according to a race- or ethnicity-based approach.