October 2015

All the papers from the October 2015 issue of Fertility and Sterility.

Peritoneal fluid in the pouch of Douglas Strategically located and affecting reproductive events

The classic paradigm describing the physiology of reproduction in women relies mainly on the hypothalamic-pituitary-ovarian axis. The ovarian steroids estradiol and progesterone control endometrial development in a cyclic pattern to achieve implantation and maintain pregnancy. This process is regulated predominantly by the endocrine and paracrine systems acting through neurons, blood vessels, and nearby cell-to-cell mechanisms. The potential contribution of free peritoneal fluid (PF) in the pouch of Douglas to the regulation of female reproductive processes has not yet been comprehensively investigated or understood in normal or pathologic conditions.