Expression of miR-29c is suppressed and inversely correlated with collagen and DNMT3A in leiomyoma. The suppression of miR-29c in leiomyoma smooth muscle cells is primarily mediated by specific protein 1, NF-kB signaling, and epigenetic modification.
MicroRNAs can be reproducibly detected in blastocyst-spent media and most likely belong to trophectoderm cells. Primary clinical data suggest testing these noninvasive biomarkers for embryo selection in IVF cycles.
Hypothyroidism after cancer treatment is associated with decreased fertility, highlighting the importance of considering other medical conditions when estimating the effects of cancer and cancer treatment on future fertility.
Indian women with polycystic ovary syndrome (PCOS) have a high prevalence of abnormal glucose tolerance, and oral glucose tolerance test significantly impacts its prevalence. Data are from a large cohort of women with PCOS attending two tertiary care centers in north India.
Dilation and curettage in women suspected of retained products of conception is associated with significantly more intrauterine adhesions and incomplete evacuation with similar reproductive outcomes compared with hysteroscopic resection.
Vasomotor and vaginal atrophy symptoms are common in community-dwelling older women but are predominantly untreated. The degree of distress caused by sexual symptoms among older women needs further exploration.
Fetal Met-Met genotype of Val158Met determines catechol-O-metyltransferase placental expression and activity in vitro and increases preeclampsia risk. However, decreased levels of 2-methoxyestradiol present in preeclampsia do not depend exclusively on this polymorphism.
The recurrent pregnancy loss endometrium shows an increased expression of inflammasome NALP-3 and ASC protein, an increased activation of caspase-1, and increased levels of IL-1b and IL-18. These are possible signs of an abnormal endometrial receptivity.
The androgen–interrupted follicle stimulating hormone protocol may improve follicular response during a microdose flare stimulation cycle in women with slow follicular growth or asynchronous follicular development.
In 1,901 IVF cycles, a cut-off value of P on the hCG day differentiating good- from poor-prognosis cycles was not identified; therefore, clinical decisions should be based on other individual circumstances.
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