Microfluidic sperm sorters are efficient and reliable for sperm preparation for in vitro fertilization and intracytoplasmic sperm injection without damaging DNA, compared with the the centrifugation and swim-up procedure.
Because germ cell neoplasia in situ is heterogeneously distributed in the testis, the AgarCyto made of the testicular sperm extraction cell suspension can diagnose a (pre-)malignancy even when the standard testicular biopsy is negative in nonobstructive azoospermia.
Reflections on “Successful elective and medically indicated oocyte vitrification and warming for autologous in vitro fertilization, with predicted birth probabilities for fertility preservation according to number of cryopreserved oocytes and age at retrieval” by Doyle et al.
Reflections on “Impact of single embryo transfer policy on perinatal outcomes in fresh and frozen cycles—analysis of the Japanese Assisted Reproduction Technology registry in Japan between 2007 and 2012” by Takeshima et al.
Reflections on “Development and validation of concurrent preimplantation genetic diagnosis for single gene disorders and comprehensive chromosomal aneuploidy screening without whole-genome amplification” by Zimmerman et al.
This study establishes a method for simultaneous comprehensive chromosomal aneuploidy screening and preimplantation genetic diagnosis for single gene disorders from the same trophectoderm biopsy using quantitative real-time polymerase chain reaction.
This randomized controlled trial could not detect a statistically significant difference in reproductive outcomes when continuous time-lapse morphokinetic data was added to conventional screening criteria for embryo selection.
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