Patients facing difficult decisions regarding disposition of their surplus embryos require further information about their options after treatment to make timely, comfortable, and informed choices.
Preimplantation genetic testing: polar bodies blastomeres trophectoderm cells or blastocoelic fluid?
The chromosome condition of DNA retrieved by blastocentesis was highly concordant with that found in trophectoderm cells, polar bodies, and blastomeres. Segmental abnormalities could also be detected in blastocoelic fluids.
Noninvasive assessment of polar bodies angle proves to be a practical tool for the selection of viable embryos and should be considered for inclusion in embryo selection parameters.
Pregnancy outcomes decline with increasing body mass index: analysis of 239127 fresh autologous in vitro fertilization cycles from the 2008-2010 Society for Assisted Reproductive Technology registry
Success rates in fresh autologous IVF cycles, including those done for specifically polycystic ovary syndrome or male-factor infertility, are highest in those with low and normal body mass indexes.
Time lapse deselection model for human day 3 in vitro fertilization embryos: the combination of qualitative and quantitative measures of embryo growth
This study presents a deselection model for human in vitro fertilization embryos independent of the insemination method, the qualitative component being more accurate when coupled with a quantitative component.
Effectiveness of semen washing to prevent human immunodeficiency virus (HIV) transmission and assist pregnancy in HIV discordant couples: a systematic review and meta analysis
Semen washing appears to be effective and safe, significantly reducing the risk of human immunodeficiency virus (HIV) transmission in HIV-discordant couples attempting to become pregnant by means of assisted reproduction.
Sperm DNA fragmentation and mitochondrial membrane potential combined are better for predicting natural conception than standard sperm parameters
Sperm DNA fragmentation and mitochondrial membrane potential combined are superior to standard sperm parameters in predicting natural conception.
Increased risk of incident chronic medical conditions in infertile men: analysis of United States claims data
Men diagnosed with male factor infertility had a significantly higher risk of adverse health outcomes in the years after an infertility evaluation.
Seminal plasma proteome reflects sperm mitochondrial defects, acrosome alterations, and DNA fragmentation. Altered proteins and biological functions were identified, and a panel of biomarkers was proposed for sperm functional traits.
Angiotensin II type 2 receptor is present in human spermatozoa and is associated with basic sperm parameters, especially motility.
We have come a long way in achieving, and preventing, pregnancy since 1966.
Reflections on “Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation” by Gronwald et al.
Reflections on “Oocytes vitrification as an efficient option for elective fertility preservation (EFP)” by Cobo et al.
Reflections on “Survey assessing obesity policies for assisted reproductive technology (ART) in the United States” by Kaye et al.
Reflections on “The role of patient education in facilitating future decisions regarding the disposition of surplus embryos” by Deniz et al.
Reflections on “Increased risk of incident chronic medical conditions in infertile men: Analysis of US claims data” by Eisenberg et al.
Effects of in vitro fertilization and maternal characteristics on perinatal outcomes: a population based study using siblings
Maternal characteristics of subfertile women are associated with a lower birthweight; in vitro fertilization treatment in itself does not additionally contribute to a lower birthweight in the offspring.
I have to say, I truly love the specialty we are fortunate enough to practice. What other area of medicine involves the laboratory and clinic so intimately intertwined, changes so rapidly, and can bring so much joy to patients? But how are we getting there? What has the trajectory of our field been? And what role do we, as clinicians, have to play in determining outcome?
Optimizing the culture environment and embryo manipulation to help maintain embryo developmental potential
Optimizing in vitro fertilization laboratory procedures is essential to improve and maintain embryo viability.
This review examines the role of LH supplementation in older women, growth hormone in poor responders, and different triggering strategies and their impact on oocyte quality and cycle outcome.