Time-lapse imaging: clearly useful to both laboratory personnel and patient outcomes versus just because we can doesn't mean we should

Fertile Battle

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Volume 109, Issue 4, Pages 584–591

Authors:

Richard J. Paulson, M.D., M.S., David E. Reichman, M.D., Nikica Zaninovic, M.S., Ph.D., H.C.L.D., E.L.D., Linnea R. Goodman, M.D., Catherine Racowsky, Ph.D.

Abstract:

Over the last 50 years, embryo culture techniques for in vitro fertilization (IVF) have continued to evolve. The latest evolution raises a controversial question—whether culturing embryos in systems which allow for undisturbed time-lapse monitoring (TLM) improve our fundamental understanding of embryogenesis, and whether that understanding can reliably translate into improved clinical outcomes (1).


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2 Comments

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Micah J Hill about 1 year ago

Thank you for this fantastic review of time-lapse imaging.  Amazingly balanced, critical, insightful and succinct!    I know we need more data, but what is the authors gut feeling on the future of time-lapse imaging?  Mainstream and here to stay or another modality that falls to the curb?

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Richard J. Paulson about 1 year ago

Thanks, Micah! It definitely adds information. Whether a lab adds that information may depend on whether it costs $1,000, $10,000 or $100,000.